Probiotic composition for improving allergic diseases
Patents no.: CN111548961A
The probiotic composition for improving allergic diseases is characterized by comprising the following components in percentage by weight:
50-95% of probiotic A and 5-50% of probiotic B;
wherein: the probiotic A is lactobacillus johnsonii which is preserved in China center for type culture Collection with the preservation number of CCTCC NO: m20191013.
The probiotics B comprises one or more of lactobacillus casei, lactobacillus paracasei, lactobacillus plantarum, lactobacillus rhamnosus and lactobacillus reuteri.
Allergic diseases such as allergic diseases, perennial allergic rhinitis and asthma are the most common allergic diseases; the probiotics are live microorganisms capable of preventing and improving allergic diseases, mainly by stimulating receptors on dendritic cells on intestinal walls and binding, activating and activating translation proteins in cells to move into nuclei to release a large amount of cytokines, effectively improving allergy symptoms by promoting the increase of secretion of interleukin 12(IL-12) and interferon gamma, and inhibiting immunoglobulin IgE by stimulating intestinal tract regulation Th1 type immune response, thereby improving allergy phenomena of Th1 and Th2 type immune response excess.
The lactobacillus johnsonii can stimulate receptors on dendritic cells on the intestinal wall and combine, activate and activate translation proteins in cells to move into nuclei to release a large amount of cytokines, effectively improve allergic symptoms by promoting the secretion increase of interleukin 12(IL-12) and interferon gamma, and inhibit immunoglobulin IgE by stimulating intestinal tract to regulate Th1 type immune response, so that the allergic phenomenon of Th1 and Th2 type immune response excess is improved; meanwhile, the compound microbial preparation has good gastric acid and bile salt tolerance and cell adhesion, can colonize in the intestinal tract of a human body for more than 60 days, and has good inhibition effect on pathogenic bacteria such as salmonella, escherichia coli, enterococcus faecalis, salmonella typhimurium and the like, thereby achieving the effects of cleaning and protecting the intestinal tract. In addition, lactobacillus casei, lactobacillus paracasei, lactobacillus plantarum, lactobacillus rhamnosus, lactobacillus reuteri, which are members of the list of strains that can be used for food and included in the ministry of health of China, cooperate to promote the function of lactobacillus johnsonii to play, and have synergistic effect.