Probioway Co., Ltd. is one of the leading manufacturers and suppliers of natural probiotics for h pylori in China, also supports custom service. Please feel free to wholesale bulk high quality natural probiotics for h pylori from our factory. Good service and reasonable price are available.
According to clinical practice in many countries over the years, probiotics can assist in the treatment of Helicobacter pylori and related gastritis, gastric ulcers and other problems, without side effects and without dependence. A research analysis showed that compared with standard therapy alone and combined therapy with helicobacter pylori probiotic treatment, the latter can increase the eradication rate of Helicobacter pylori by about 10%, and also reduce the occurrence of adverse reactions caused by antibiotics (such as diarrhea, nausea, etc.).
Main Ingredients
L.johnsonii LBJ456®, L.acidophilus HH-LA26, L.helveticus HH-LPH17, L.casei PB-LC39, B.longum
HH-BL18, B.lactis HH-BA68, B.bifidum HH-BB27, S.thermophilus HH-ST08.
Other Ingredients
For capsule: fructooligosaccharides, Hericium erinaceus extract, microcrystalline cellulose, silica.
For powder: inulin, stachyose, galactooligosaccharides, erythritol, fructooligosaccharides, sea buckthorn powder, Hericium erinaceus extract.
Patents：
CN114259055A
lactobacillus plantarum HH-LP78
The invention discloses a composition for antagonizing helicobacter pylori, which comprises lactobacillus plantarum (A)Lactobacillus plantarum HH-LP78
Package Specification
- High Potency Probiotic Powder: 1/5/10kg per bag, 200 billion CFU/g
- For Probiotic Capsule: 20 billion CFU/capsule, 30/60 capsules per bottle
- For Compound Probiotic Powder: 20 billion CFU/sachet, 30/60 sachets per box.
Storage and Shelf Life
The recommended storage temperature of High Potency Probiotic Powder is below -18℃, the shelf life is 24 months.
The Probiotic Capsule and Compound Probiotic Powder can be stored in a cool and dry place, the shelf life is 24 months.
Dosage
Recommended daily intake for adults: 4 0 billion CFU/day.
Key Features
- Safety of Probiotic Strains: All strains in this formula were clearly sourced and identified by 16S rRNA and whole genome sequencing, free from GMOs and non-hemolytic. Acute and 28-day oral toxicity tests in mice showed no adverse effects or deaths, with no significant differences in weight, organ indices, or blood biochemistry between the test and control groups. Overall, the strains are highly safe.
- Scientific Evidence: the product's efficacy has been validated both in vitro and in vivo, utilizing mice model for comprehensive mechanistic verification.
Mechanism of Action
Probiotics are live microorganisms that confer beneficial effects on the host by colonizing specific sites and modulating the composition of local microbiota. With recent advancements in microbiology, the application of natural probiotics for h pylori eradication therapies has emerged as a significant research focus. The mechanisms through which probiotics exert effects against H.pylori infection exhibit considerable complexity and diversity. Current research indicates the following principal mechanisms:
①Secretion of antimicrobial compounds, including bacteriocins, lactic acid, and hydrogen peroxide, which inhibit Hp proliferation and growth, thereby contributing to its clearance;
②Production of anti-adhesive substances that reduce the adhesion of Hp to gastric epithelial cells;
③Upregulation of small intestinal binding protein expression, indirectly facilitating the restoration of gastric mucosal permeability;
④Suppression of Hp-induced release of pro-inflammatory cytokines such as interleukin-1β (IL-1β)and interleukin-8 (IL-8), consequently attenuating its pathogenicity. The strains employed in this formulation-L.johnsonii LBJ456®, L.acidophilus HH-LA26, L.helveticus HH-LPH17, L.casei PB-LC39, B.longum HH-BL18, B.lactis HH-BA68, B.bifidum HH-BB27, S.thermophilus HH-ST08-demonstrate efficacy against Hp through the following mechanisms:
①Inhibition of H. pylori growth and proliferation;
②Reduction in urease enzyme activity secreted by H. pylori.
In Vitro Inhibition of H.pylori
pylori and the composite probiotic powder were co-cultured for 48 hours. Viable H. pylori counts in the culture media of both the experimental group (H. pylori + composite probiotic powder) and the control group (H. pylori alone) were enumerated at 0, 8, 12, 24, and 48 hours. Compared to the control group(Table1), the growth of H. pylori in the experimental group was significantly inhibited. By the endpoint of the culture period (48 hours), the viable bacterial count in the experimental group exhibited a 4 log reduction relative to the control group.
Animal trial of natural probiotics for h pylori
Healthy mice were inoculated with H. pylori via oral gavage to establish infection. Eleven days
post-infection, the mice received a 28-day regimen of composite probiotic powder(1×10
8CFU/day)administered by daily gavage. Gastric H. pylori colonization levels were quantified at three time points:
baseline (post-infection/pre-treatment), after 14 days of treatment, and after 28 days of treatment. As illustrated in Figure 2, the composite probiotic powder significantly reduced gastric H. pylori burden compared to untreated controls. Furthermore, the reduction exhibited a clear duration-dependent effect, with progressively lower bacterial loads observed following extended treatment periods. These findings demonstrate that the composite probiotic powder significantly inhibits H. pylori colonization in vivo.
FAQs About Natural Probiotics for H. pylori
1. What Are Natural Probiotics for H. pylori?
Natural probiotics for H. pylori are beneficial microorganisms studied for their potential to support digestive health and maintain a balanced gut microbiome in people with Helicobacter pylori infection. Certain probiotic strains may be used as complementary ingredients in digestive health supplements.
2. What Are the Best Probiotics for H. pylori?
Some of the most commonly studied probiotics for H. pylori include specific strains of Lactobacillus, Bifidobacterium, and Saccharomyces boulardii. Their potential benefits vary by strain, so clinical evidence and product quality should be considered when selecting a probiotic.
3. Can Lactobacillus Help with H. pylori?
Certain Lactobacillus strains have been studied for their potential to support gastrointestinal health and influence H. pylori-related outcomes. Some may also help reduce digestive side effects associated with standard eradication therapy. However, their effects are strain-specific, and they cannot replace prescribed treatment.
4. Is Bifidobacterium Good for H. pylori?
Bifidobacterium strains are among the probiotic ingredients studied for Helicobacter pylori-related digestive health. They may help support gut microbiome balance, particularly when used as part of a properly designed probiotic formulation. Their effectiveness depends on the specific strain and application.
5. Can Probiotics for Helicobacter pylori Replace Antibiotics?
No. Probiotics for Helicobacter pylori are not a replacement for standard antibiotic-based eradication therapy. They may be considered complementary supplements in some treatment plans, but they should not be used alone to eliminate H. pylori.
6. Can I Take Probiotics During H. pylori Treatment?
Certain probiotic strains may be taken alongside standard H. pylori treatment under healthcare professional guidance. Research suggests that some probiotics may help reduce treatment-related gastrointestinal side effects and support digestive comfort.
7. What Should Buyers Look for in an H. pylori Probiotic Supplement?
When sourcing an H. pylori probiotic supplement or developing a related product, buyers should evaluate:
- Strain identification: Confirm the exact strain name and identification documents.
- CFU count: Check the viable count per gram or per serving.
- Research support: Review available strain-specific research.
- Product stability: Evaluate viability during processing and storage.
- Quality documentation: Request COA and microbiological testing reports.
- Formulation compatibility: Confirm whether the probiotic is suitable for the intended product format.
Hot Tags: natural probiotics for h pylori, manufacturers, factory, custom, wholesale, bulk, best probiotics for men, cranberry probiotics, good gut bacteria supplement, inflammation probiotics sachet, Oral Probiotics, Probiotic Supplements for children
