Common dosage forms of probiotics preparations
The dosage forms of probiotic preparations are mainly in solid forms such as powders, granules, capsules, and tablets. In recent years, new preparations of probiotics such as oil drops have also emerged. The emergence of new preparations is crucial to the innovation and development of the probiotics market.
probiotics Powder
The probiotic food production process is usually to highly concentrate the probiotic bacteria liquid, collect the probiotic bacteria, add the centrifuged bacteria to a freeze-drying protective agent, freeze-dry to obtain the bacteria powder, and make it into a probiotic preparation product. Powder probiotic preparation products have the advantages of easy production, convenient storage and good absorption.
probiotics Granule
Granular probiotic preparations are usually prepared by crushing, mixing, granulating, drying, and packaging freeze-dried bacteria powder and auxiliary materials such as starch, sucrose powder, and maltodextrin. Granules need to pay attention to the solubility of the product; in addition, the temperature of the water used for brewing and the storage time will affect the number of viable bacteria of probiotics.
Probiotics Capsule
Capsule probiotic preparations are divided into two types: hard capsules and soft capsules. The dosage forms of probiotic hard capsules and soft capsules have the characteristics of neat appearance and can mask the unpleasant taste of the finished product. However, the use of capsule preparations in infants and young children has certain limitations.
probiotics tablets
Probiotics tablets are obtained by mixing probiotics with excipients through powder direct compression method or wet granulation technology. Tablets are easy to eat and carry for consumers.
Using dry granulation technology and tabletting technology, granules are prepared from auxiliary materials such as glucose, lactose, microcrystalline cellulose, and skimmed milk powder, and then mixed with active ingredients probiotic powder and magnesium stearate for tabletting, and finally probiotics are obtained tablet.
However, tablet-type probiotic preparations need to go through a drying step during the production process. Usually, excessive temperature is not conducive to the survival of probiotics and directly affects the quality of probiotic preparations.
probiotic drops
The production process of drop-type probiotic preparations is complicated, and the process requirements for manufacturers are relatively high. Choose high-quality food oil, such as sunflower oil, which can isolate the oxygen and water from the probiotic bacteria. Even at room temperature, it can preserve the number of viable bacteria for a long time. It is currently an ideal probiotic formulation .