1. What is Bacillus coagulans?
Bacillus coagulans is rod-shaped with blunt ends. It is a Gram-positive bacterium, catalase-positive, and the spores are end-bearing without flagella. The optimal growth temperature is 45~50℃, and the optimal pH value is 6.6~7.0. Bacillus coagulans produces both lactic acid and spores. It has the probiotic effects of general lactic acid bacteria in maintaining intestinal microecological balance, stimulating immunity, and improving the digestive function of animals. It also has anti-acid-alkali, anti-cholinergic, anti-heat, and anti-inflammatory properties. Resistance to dryness and other stresses.
2. Characteristics of Bacillus coagulans
Bacillus Coagulans is a Gram-positive bacterium with a rod-shaped cell body and blunt rounded ends. It is single, paired, and a few are in the shape of short chains. The buds are terminal and have no flagella. The optimal growth temperature is 37 ~45℃, the optimal pH value is 66~7.0. It can decompose sugars to produce L-lactic acid. It is a homolactic acid fermentation bacterium. This bacterium can produce spores and is highly resistant to the environment. Bacillus coagulans will not be inactivated after being treated at 90°C, 10min and 100°C, 5min; when dried at room temperature, the solid viable bacteria preparation can be stored for 3 to 5 years without significant reduction in the number of viable bacteria;Bacillus coagulans can survive for more than 4 weeks in 1%~7% NaC1 solution, and can survive for 1 month in 8% NaC1 solution; it can still survive at pH 1.0, but Bacillus coagulans can survive at low pH Under certain conditions, its stress resistance will decrease. For example, under acidic conditions (pH 4.0), Bacillus coagulans spores have little tolerance to heat and their growth is inhibited. Compared with other beneficial bacteria such as Bifidobacterium and Lactobacillus, Bacillus coagulans can tolerate the dual effects of gastric acid and digestive enzymes and colonize the intestines. They can quickly recover in the intestines and become viable bacteria again, thus exerting their protective effect on the intestines.
3. Physiological functions of Bacillus coagulans
After Bacillus coagulans enters the stomach orally, it is activated under the action of gastric juice, the spore coat expands, the shape of the spores increases, and the metabolism increases as the water content increases. When Bacillus coagulans enters the duodenum, its spores germinate into vegetative cells. After entering the small intestine, vegetative cells begin to grow and reproduce, with one generation taking about 30 minutes. Bacillus coagulans is a facultative anaerobic bacterium. When it enters the intestine, it consumes free oxygen to reproduce in the intestine, which is beneficial to the growth of anaerobic microorganisms lactobacilli and bifidobacteria, thereby regulating the balance of microbial flora in the intestine and improving The body's immunity and disease resistance,Reduce the occurrence of intestinal diseases. Bacillus coagulans also secretes amylase and protease during intestinal reproduction to promote the body's digestion and absorption of nutrients: the B vitamins, amino acid short-chain fatty acids and other substances it produces can increase the peristalsis speed of the small intestine, thereby improving Digestive function of the intestines. In addition, after Bacillus coagulans settles in the intestine, it can also produce a large amount of antibacterial substances such as coagulin and L (+) lactic acid that inhibit harmful bacteria. Therefore, it has a certain therapeutic effect on gastrointestinal inflammation.