Probioway Anti Inflammatory Probiotics is specially formulated probiotics for inflammation support. This probiotic formula contains 30 Billion CFU of one patented and scientifically-proven anti inflammatory probiotic strains L.johnsonii LBJ456 shown to:
√ Promote health infammatory response**
√ Reduce oxidative stress and genotoxicity**
Other Ingredients: inulin, stachyose, galactooligosaccharide, fucoidin, tea polysaccharide,citrus extract,multi-vitamins.
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Supplement Facts |
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Serving Size: 1 Packet Servings Per Container: 20 |
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Amount Per Serving %DV* |
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Amount Per Serving %DV* Probiotic Blend 30 Billion CFU L.johnsoniiLBJ456, B.lactis HH-BA68, L.acidophilus HH-LA26 L.reuteri PB-LRO9 B.longum HH-BL18, L.casei PB-LC39 |
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*Daily Value(DV) not established |
Packing:
30 Billion Organisms Per Packet
Net Weight:40g(2gx20 Packets)
Suggested use: take the powder after meals (best within 30-60 mins) with water or juice(<45℃).
Take 1 packet once or twice daily.
Possible benefits:
- Reduces levels of pro inflammatory factors in general arthritis, including blood, liver, and spleen
- Eliminate inflammation caused by pathogenic bacteria
- Reduce chronic inflammation
- Reduce oxidative stress
Lactobacillus johnsonii LBJ 456 exerts its anti-inflammatory effect through multiple mechanisms, such as reducing the level of pro-inflammatory cytokines, increasing the level of anti-inflammatory cytokines, regulating the balance of intestinal flora, and enhancing intestinal barrier function. These mechanisms of action work together on the host body, helping to reduce inflammatory responses, promote recovery and repair, and provide new ideas and hopes for the treatment of various diseases.
Lactobacillus johnsonii (LBJ 456)
- Deposit No.: PTA-124205 (US), CCTCC M20191013
- Patents: NO.: WO2014130540(International), EP2958575A1(Europe), US10413577B2(USA) and US10028983B2(USA)
- Characteristics:
Gene identified, patented deposited, trial papers published,Better gastric acid and
bile salt tolerance than normal bacteria,Better colonization,Good inhibitory effect for Pathogens.
Applications:
This strain can be used as probiotics for gut inflammation, probiotics for joint inflammation, probiotic for intestinal inflammation and probiotic for stomach inflammation.
clinical and experimental evidence
Animal experiments: In animal experiments, Lactobacillus johnsonii LBJ 456 has been proven to have significant anti-inflammatory effects. It reduces pro-inflammatory cytokine levels in the blood of mice and induces the body to produce anti-inflammatory factors.
Application prospects: Based on its unique anti-inflammatory properties, Lactobacillus johnsonii LBJ 456 has broad application prospects in adjuvant surgical therapy, combined chemotherapy treatment, and supportive care during radiotherapy. At the same time, it can also serve as a companion to targeted therapy and immunotherapy to improve treatment efficacy and reduce the risk of recurrence.


The mechanism of action of Lactobacillus johnsonii LBJ 456 in anti-inflammatory is mainly based on its ability to regulate the host immune system and reduce systemic inflammation. The following is a detailed description of its mechanism of action:
1. Reducing the level of pro-inflammatory cytokines
Mechanism description: Lactobacillus johnsonii LBJ 456 can reduce the level of pro-inflammatory cytokines in the host, such as IL-1β and IFN-β. These pro-inflammatory cytokines play a key role in the inflammatory response, and their overexpression often leads to an aggravation of the inflammatory response.
Effect: By reducing the level of these pro-inflammatory cytokines, Lactobacillus johnsonii LBJ 456 helps to reduce the inflammatory response, thereby protecting the host tissue from damage.
2. Improving the level of anti-inflammatory cytokines
Mechanism description: At the same time, the strain can also increase the level of anti-inflammatory cytokines, such as TGFβ and IL-10. These anti-inflammatory cytokines play an important role in inhibiting the inflammatory response and help restore the body's immune balance.
Effect: By increasing the level of anti-inflammatory cytokines, Lactobacillus johnsonii LBJ 456 can further enhance its anti-inflammatory effect and promote the body's recovery and repair.
3. Regulate the balance of intestinal flora
Mechanism description: The balance of intestinal flora is essential for host health. As a kind of probiotic, Lactobacillus johnsonii LBJ 456 can regulate the balance of intestinal microecology by interacting with intestinal flora.
Effect: The improvement of intestinal flora balance helps to reduce the growth of harmful bacteria and increase the number of beneficial bacteria, thereby reducing intestinal inflammatory response and promoting intestinal health.
4. Enhance intestinal barrier function
Mechanism description: The intestinal barrier is the first line of defense to prevent harmful substances from entering the body. Lactobacillus johnsonii LBJ 456 can enhance the barrier function of intestinal epithelial cells and improve the integrity of the intestinal barrier.
Effect: This helps to reduce the stimulation and damage of harmful substances to the body and further reduce the inflammatory response.
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