Allergic diseases refer to a type of disease in which the body produces a large number of allergic antibodies after being exposed to one or more allergens (allergens), thereby causing tissue or organ dysfunction or damage. It mainly includes allergic rhinitis, asthma, and allergic rhinitis. Atopic dermatitis, allergic gastrointestinal diseases food allergies, etc.
A large number of scientific studies have shown that intestinal flora is related to the occurrence of allergic diseases. The intestinal flora of patients with allergic diseases has unique distribution and abundance, such as the typical inverted distribution of Bifidobacteria and Bifidobacteria. Daily dietary supplementation of probiotics can effectively improve the distribution of intestinal microecology and correct the imbalance of intestinal flora, thereby preventing and improving allergic diseases.
H&H Bioengineering Duofu Probiotic is a probiotic specially developed for people with allergies. It contains high-content star strains: Lactobacillus reuteri, Lactobacillus rhamnosus, and Lactobacillus plantarum; it also contains selected strains: Bifidobacterium longum, Lactobacillus paracasei, Bifidobacterium lactis. Its mechanism of action is as follows:
Correct Th1/Th2 balance: Th1/Th2 cell imbalance is closely related to the occurrence of allergic inflammation. Studies have shown that Lactobacillus rhamnosus is beneficial to regulating the production of Th1 and Th2 cytokines, combating Th1/Th2 cell imbalance, inhibiting excessive activation of Th2, and reducing allergic symptoms.
Promote Treg activation: A relative deficiency of Tregs can lead to allergic reactions. Studies have shown that Bifidobacterium lactis can provide signals for Treg cell differentiation and induce intestinal barrier maturation, thereby reducing the incidence of allergic reactions. Supplementing a certain amount of Bifidobacterium longum, Lactobacillus paracasei, and Lactobacillus reuteri can reduce blood IgE levels, induce the differentiation of Th cells into Treg cells, and even inhibit the differentiation of Th cells into Th2 cells, thereby alleviating allergic symptoms in the respiratory system.
Anti-inflammatory effect: An in vitro experiment used the Transwell system to verify the anti-inflammatory effect of a mixed probiotic preparation (Lactobacillus rhamnosus, Bifidobacterium lactis, and Bifidobacterium longum). The results showed that the preparation could significantly increase anti-inflammatory cells. The production of factor IL-10 and reduction of the secretion of the main pro-inflammatory cytokines IL-1β and IL-6 prove for the first time that probiotics can promote the M2 phenotype of macrophages, thereby alleviating and treating allergic inflammatory reactions. effect.