Science and Technology Innovation Center Yue Weifeng January 12, 2024
An excellent strain of bacteria can only be commercialized after rigorous screening, isolation, identification, laboratory functional verification, and even clinical safety and effectiveness verification. It also has long-term development potential. Specifically, the following points must be met:
1. The source of the strain is clear
The traceability of the source of the strain ensures the naturalness and safety of the strain. According to the probiotic industry group standards, engineered strains are temporarily not qualified for consumption. This is also for the genetic safety and human safety of natural microorganisms.
2. The strain has been identified and collected
The genome identification of the strain can help people understand the strain at the species level and facilitate further exploration of the efficacy of developing strains. At the same time, it also ensures that the strain can officially enter the national strain bank and be recognized by professional institutions.
3. Has high biological activity and high viable bacterial count
As a good probiotic strain, it must ensure high biological activity and reach the level of industrial fermentation in terms of proliferation and metabolism, to ensure industrial application. At the same time, the efficacy and stability of this strain can be ensured in subsequent product development and transportation.
4. Good acid resistance and bile salt resistance
The most important thing for probiotic products to work is to ensure that a sufficient number of viable bacteria enter the intestine and achieve colonization. Probiotics must undergo a series of harsh conditions before being taken: decomposition by various enzymes in oral saliva, corrosion by gastric acid and bile salts, enzymatic decomposition of intestinal peristalsis, etc. Therefore, a good probiotic strain must be able to function in the intestinal tract in a highly active state under various harsh body conditions.
5. Clear functions, safe and effective
A good probiotic strain should have clear functions when used as a product so that it can improve health. At the same time, the function of this strain has been confirmed at least at the animal level, and its safety has been verified in humans.
Generally speaking, first of all, a good strain must have safety certification, good biological activity, and a high number of viable bacteria; it must be able to resist damage from human gastric acid and bile salts, and then reach the intestinal tract in the form of viable bacteria. And play a role in providing probiotic and healthy functions. Only those strains that meet the above conditions are good. At the same time, we should also pay attention to individual differences in the impact of probiotics on human health. The most important thing is the ones that are suitable for your physical condition. Therefore, when choosing probiotics, you must consider whether they are suitable for your intestinal structure and eating habits.
